[PDF][PDF] Accumbal dopamine release tracks the expectation of dopamine neuron-mediated reinforcement

DP Covey, JF Cheer - Cell reports, 2019 - cell.com
dopamine signaling drives and encodes reward learning and seeking, Covey and Cheer
recorded nucleus accumbens dopamine … baseline following the elimination and reintroduction …

Mesolimbic dopamine projections mediate cue-motivated reward seeking but not reward retrieval in rats

B Halbout, AT Marshall, A Azimi, M Liljeholm… - Elife, 2019 - elifesciences.org
… inhibiting dopamine inputs to nucleus accumbens, but not medial prefrontal cortex. Inhibiting
dopamine neurons spared the suppressive effect of reward devaluation on reward seeking, …

[HTML][HTML] Corticosterone attenuates reward-seeking behavior and increases anxiety via D2 receptor signaling in ventral tegmental area dopamine neurons

B Peng, Q Xu, J Liu, S Guo, SL Borgland… - Journal of …, 2021 - Soc Neuroscience
… treatment suppresses excitability and synaptic transmission onto VTA dopamine neurons. …
Together, CORT-induced neuronal disruptions in a key region mediating reward-seeking …

Learned avoidance requires VTA KOR-mediated reductions in dopamine

MA Robble, ME Bozsik, DS Wheeler, RA Wheeler - Neuropharmacology, 2020 - Elsevier
dopamine system is known to be essential for rewarddopamine neurons and electrochemical
monitoring of terminal … aversive stimulus and learned suppression of behaviors associated …

Negative allosteric modulation of CB1 cannabinoid receptor signaling suppresses opioid-mediated reward

V Iyer, C Rangel-Barajas, TJ Woodward… - Pharmacological …, 2022 - Elsevier
… The circumscribed allosteric effects of GAT358 may result in endocannabinoid-mediated
self-regulation of dopaminergic neurons that reduces drug reward [80]. Such mechanisms …

Serotonergic regulation of the dopaminergic system: Implications for reward-related functions

E Courtiol, EC Menezes, CM Teixeira - Neuroscience & Biobehavioral …, 2021 - Elsevier
… From these studies, it appears that activation of this pathway can lead to reinforcement
learning mediated through the excitation of dopaminergic neurons by serotonergic neurons co-…

[HTML][HTML] Seeking motivation and reward: Roles of dopamine, hippocampus, and supramammillo-septal pathway

AJ Kesner, CB Calva, S Ikemoto - Progress in neurobiology, 2022 - Elsevier
… Reinforcement learning and goal-seeking behavior are thought to be mediated by
midbrain dopamine neurons. However, little is known about neural substrates of curiosity and …

Females are less sensitive than males to the motivational-and dopamine-suppressing effects of kappa opioid receptor activation

SM Conway, D Puttick, S Russell, D Potter… - …, 2019 - Elsevier
… males to KOR-mediated decreases in brain stimulation reward, … in KOR-mediated suppression
of dopamine, we used fast … less effective in suppressing evoked NAc dopamine release in …

A brain on cannabinoids: the role of dopamine release in reward seeking and addiction

KZ Peters, EB Oleson, JF Cheer - Cold Spring …, 2021 - perspectivesinmedicine.cshlp.org
… responses to both reward delivery and reward-predictive … regulation of dopamine signaling
mediating reward-directed … GABA suppression results in disinhibition of the dopamine neuron

Synaptic regulation by OPRM1 variants in reward neurocircuitry

D Popova, N Desai, JA Blendy… - Journal of …, 2019 - Soc Neuroscience
… effects on mEPSCs, which were mediated by presynaptic GABA B receptors. … dopamine
neuronal firing via presynaptic regulation. The A118G SNP affects MOR-mediated suppression